Best Collagen Types 1 & 3 Powder 200G
Code: DRB-00203
Size: 200G
MSRP: $ 19.99
Does Not Contain: milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, or preservatives.

Best Collagen Types 1 & 3 Powder 200G
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- Science-based nutrition
- Dietary supplement
- Essential structural support for hair, skin, nails tendons, ligaments and bones*
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Collagen is the major structural protein in connective tissue and the most abundant protein in the human body. It is responsible for maintaining the strength and flexibility of bones, joints, skin, tendons, ligaments, hair, nails, blood vessels and eyes, among other tissues throughout the body.
Best Collagen Types 1 & 3 contains pure collagen protein, providing the fundamental building blocks for growth and maintenance of healthy tissues.* Taken as a supplement, this product provides the body with the raw material needed to support the strength and integrity of essential structures.* Best Collagen Types 1 & 3 is enzymatically hydrolyzed into component amino acids with a low molecular weight for optimal absorption and utilization by the body.*
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Suggested Use: Dissolve 1 scoop of powder in a small amount of water or juice. Add an additional 6-8 oz. of liquid, mix well, and drink on an empty stomach at least 30 minutes before meals. Do not mix with other protein powder supplements.
Supplement Facts Serving Size: 1 scoop (6.6 grams) Serving per container: Approximately 30 servings Amount Per Serving         %DV Sodium                                                      20 mg              1% -------------------------------------------------------------------------------------------- Collagen Types 1 & 3                                 6,600 mg              †-------------------------------------------------------------------------------------------- †Daily Value not established.
Other Ingredients: None.
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Contains nothing other than listed ingredients
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7.1 oz. (200 grams)
Collagen is the major structural protein in connective tissue and the most abundant protein in the human body. It is responsible for maintaining the strength and flexibility of bones, joints, skin, tendons, ligaments, hair, nails, blood vessels and eyes, among other tissues throughout the body.
Best Collagen Types 1 & 3 contains pure collagen protein, providing the fundamental building blocks for growth and maintenance of healthy tissues.* Taken as a supplement, this product provides the body with the raw material needed to support the strength and integrity of essential structures.* Best Collagen Types 1 & 3 is enzymatically hydrolyzed into component amino acids with a low molecular weight for optimal absorption and utilization by the body.* Vitamin C has been added to the tablet form, as it is an essential nutrient required for collagen synthesis by the body.*
Collagen Structure
Collagen is a long, fibrous protein that makes up the extracellular matrix of connective tissue. The mesh of fibers that are formed by adjoining collagen molecules in tissues contributes to its structural and strength-giving properties. Conformationally, collagen is arranged in a triple helix, lending strength and integrity to the fiber matrix. Collagen molecules are particularly rich in four amino acids: glycine, proline, hydroxylysine and hydroxyproline. While several other amino acid residues are contained within collagen, these four amino acids make up more than 50% of its structure.
Essential Structural Support for Hair, Skin, Nails, Tendons, Ligaments and Bones*
There are a number of different types of collagen; the most prevalent two in the human body are types I and III. In fact, type I collagen is the most abundant protein in the human body – it is present in almost every type of tissue.1 Bone contains almost exclusively type I collagen. The collagen network in bone confers structural strength to bone tissue and prevents bone fragility. Deficient or defective collagen production, as can occur with aging, is a risk factor for fractures and other bone deformities.2
Type I collagen is also the major protein found in skin connective tissue where it is responsible for providing skin with its tensile strength and resiliency.3 Type III collagen is found at high levels in cardiovascular tissue and also in newly developing skin. It is essential for the proper development of the cardiovascular system and skin tissue. Types I and III collagen are often found together in the same tissues, as each form complements the structural integrity of the other.
Vitamin C is required for the synthesis of collagen and participates at nearly every step of the process. The critical role of vitamin C involves preventing the inactivation of several key enzymes required for collagen biosynthesis. Studies suggest that vitamin C enhances the function of fibroblasts and promotes an increased level of collagen deposition by these cells in human tissue.4 Vitamin C also functions to promote the strengthening of the collagen matrix and supports an increased level of collagen density in organs and tissues. These effects of vitamin C also suggest that intake levels of this vitamin may be inadequate as we age. As oxidative stress in tissues increases with age, there is an increased requirement for this crucial antioxidant vitamin to promote optimal collagen production.
Collagen and Normal Aging
Collagen synthesis is a continuous process throughout life. Collagen is essential for growth and repair, and is also produced during the process of wound healing. Rejuvenation and renewal of every tissue throughout the body requires the production of newly synthesized collagen. However, this process can become less efficient as we age, leading to decreased renewal of old tissue.5 This is manifested internally as a lessened efficiency of organ and tissue function. However, the most obvious manifestation of this process occurs externally. The most visible tissue in the body, and the most obvious place to observe the effects of aging, is the skin. As the skin ages, the levels of type I and III collagen, as well as elastin, decrease in the dermis, resulting in the loss of elasticity.3 This results in the appearance of wrinkles, fine lines and an aged look, as well as various skin blemishes and discoloration. The rate at which this occurs depends upon many factors including genetics, metabolic processes, hormonal changes and environmental exposures, such as to UV radiation from the sun or smoking tobacco (both of which can lead to increased break down of collagen in the skin and/or decreased synthesis of new collagen).6,7
Oxidative stress is thought to play a large role in the aging process as well. In general, while we are youthful, our body has the ability to combat the internal and external effects of oxidative stress more efficiently. However, as we age, and due to the genetic, metabolic and environmental changes mentioned above, often the amount of free radical production outpaces the antioxidant defenses of our body's organs and tissues.
Since the body has become less efficient at dealing with the various stressors it encounters on a daily basis, it is even more critical to help it by providing the antioxidants and structural building blocks it needs to continually rejuvenate itself. Of course, a healthy diet that is rich in fruits and vegetables, as well as targeted nutritional supplementation, provide a wide range of antioxidants that the body can use to bolster its defense mechanisms. Furthermore, supplementing with Best Collagen can benefit the body by providing structural support.
Best Collagen Types 1 & 3 contains the necessary building blocks for collagen renewal and the cofactors that enhance tissue strength and integrity. Replenishing the structural building blocks and antioxidants on a consistent basis can lead to healthy, vibrant and youthful tissue and organ function. Efficient collagen renewal also leads to strong, healthy bones. Outwardly, this manifests as supple skin with a decrease in wrinkles and blemishes, and an increase in strength and elasticity.
- Jensen LT, Høst NB. Cardiovasc Res. 1997 Mar;33(3):535-9.
- Vashishth D. Curr Osteoporos Rep. 2007 Jun;5(2):62-6.
- Callaghan TM, Wilhelm KP. Int J Cosmet Sci. 2008 Oct;30(5):313-22.
- Murad S, Grove D, Lindberg KA, Reynolds G, Sivarajah A, Pinnell SR. Proc Natl Acad Sci U S A. 1981 May;78(5):2879-82.
- Sørensen LT. Hernia. 2006 Dec;10(6):456-61.
- Chung JH, Seo JY, Choi HR, Lee MK, Youn CS, Rhie G, Cho KH, Kim KH, Park KC, Eun HC. J Invest Dermatol. 2001 Nov;117(5):1218-24.
- Yin L, Morita A, Tsuji T. Exp Dermatol. 2003;12 Suppl 2:51-6.
| Q1. |
Is it OK to take Collagen Type 2 with Collagen Types 1 and 3, or do they compete with each other for absorption? |
| A1. |
They do not compete. To some extent, both would be digested in the GI tract and provide building blocks to the body for connective tissue support.
Type I is the most abundant collagen in the body and is in high concentrations in blood vessels, tendons, skin and muscle tissue.
Type III is used by the body for quick repairs and is often a precursor to type I.
Type II is the major component of hyaline cartilage in joint tissue.
Taking all together would likely yield an increase in the building blocks that are needed by the body to support connective tissue in many different areas. |
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| Q2. |
What is the raw material of the Best Collagen Types 1&3? |
| A2. |
Hydrolyzed Bovine Collagen. |
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| Q3. |
Is fish collagen superior to animal source collagen? |
| A3. |
Some think that fish collagen is superior to animal source. Bovine collagen is very different from fish collagen. In fact, fish collagen is even more different from human collagen. Humans have a skin that has fibers that intertwine to allow for a thick dermis and epidermis layer. The distribution of fibers and microfibers in mammals is very different than that of fish. Within the mammal family even though there exist differences we are united through genetic origins. Whereas mammals and fish are totally different, fish possess skin that does not form collagen fibers like the mammals. They don't support a dermis layer, they only possess an epidermis layer. Also, fish collagen is a poor transporter of moisture (water). Common sense tells us that if fish collagen were a good transporter of moisture (water) fish would not be able to live in water. Mammal collagen is a very good transporter of water this is why mammals cannot stay in water very long, especially salt water. In conclusion, fish collagen has low hydrating properties based on the fish’s origin wherein they have actually formed membranes that do not allow the penetration of water. The human (mammal) collagen is completely the opposite, it permits the transportation of moisture (water) toward the epidermis plus the mammal also has a dermis layer which fish do not. |
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| Q4. |
I am somewhat confused on how to take the DRB products. On many of the labels the Suggested Adult Use will list something along the lines of: Take 2 capsules daily, but it does not state whether they should be taken together or separately. What is the correct usage? |
| A4. |
Unless otherwise specified on the label, the product may be taken together or separately. |
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| Q5. |
Is there a limit to how many vitamins can be taken safely in one day? |
| A5. |
While our bodies need vitamins and minerals, like other things, if taken in large amounts they may adversely affect health. Large amounts of anything can be toxic. It is important to follow all label directions and discuss any concerns with your physician. |
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| Q6. |
What are the other ingredients and why are they used? |
| A6. |
These are used as flow agents and aid in the production to keep the machinery running smoothly and the capsules filling correctly. Similarly for the croscarmellose sodium, which is cellulose (sourced from the cell walls of green plants), and is used to help disintegrate the tablet in the stomach. |
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| Q7. |
Since Doctor's Best does not manufacture its supplements, how are the purity and integrity of supplements verified? In addition, how are your prices lower than other brands? Does this mean that quality is being compromised? |
| A7. |
Doctor's Best supplements are manufactured in the US at cGMP (current Good Manufacturing Practice) certified facilities. All of our manufacturers and suppliers go through our vendor qualification program, which includes inspections and testing, before we agree to work with them. Our finished products have also been tested at the raw material level, in process, and as a finished product to ensure safety and quality. We place the highest importance on safety and quality and do not compromise for the sake of a better price point. The price points are lower because of production size and the overall business structure. We also place great importance on making our supplements available and affordable to those who need them most. |
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| Q8. |
What is HPLC? |
| A8. |
HPLC stands for "High Performance Liquid Chromatography." This is an analytical lab testing method that is used to quantify the active ingredients. It is considered to be a very sensitive and accurate test. HPLC testing is a tool recognized as a quality benchmark for herbal extracts. |
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| Q9. |
Are solvents used in manufacturing Best Collagen Types I & III? |
| A9. |
No, there are no solvents used during the production of Best Collagen Types I & III. |
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| Q10. |
Can I give my child Best Collagen Types I & III? |
| A10. |
Human consumption of collagen (type I, II and III) as a food has occurred for thousands of years in the form of various components of meat. Many types of collagen are considered GRAS (generally recognized as safe) by FDA, including the most commonly known one, gelatin (a hydrolysate of animal collagen). Furthermore, although not specific to children, a search of the literature reveals no concerns from the consumption of collagen and collagen is considered safe, and lacking toxicity by the scientific community (Moskowitz 2000, Benito-Ruiz et al 2009). |
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DOCTOR'S BEST INTRODUCES Best Collagen Types 1 & 3, 180 Tablets & Best Collagen Types 1 & 3 Powder, 200G
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