Best MSM Powder 250G
Code: DRB-00076
Size: 250 G
MSRP: $ 16.99
Does Not Contain: milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives.

Best MSM Powder 250 Grams
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Suitable for vegetarians
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- Science-based nutrition
- Dietary supplement
- Maintains healthy connective tissue*
Best MSM supplies pure crystalline MSM (methylsulfonylmethane), a naturally-occuring source of organic sulfur that is easily absorbed and used by the body. Taken up from the soil by plants, MSM found in foods is largely lost during food processing, storage and cooking.
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MSM supports organ and joint function by donating sulfur for maintenance of healthy connective tissue.* MSM helps keep skin, hair and nails healthy by donating sulfur for products of keratin, a fibrous protein. Supports joint function.*
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Suggested Adult Use: Take 1 to 4 grams (1000-4000 mg) daily in divided doses of 1/4 to 1/2 teaspoon. Mix with 8 ounces water or juice.
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Supplement Facts Serving Size: 1/4 teaspoon Serving per container: 250 servings Amount Per Serving %DV Methylsulfonylmethane 1 gram (1000 mg) †OptiMSM® --------------------------------------------------------------------------------------------------------- †Daily Value Not Established.
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Other ingredients: none.
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Contains nothing other than listed ingredients.
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250 Grams
Best MSM and Best MSM Powder contain pure MSM (methylsulfonylmethane), a white crystalline substance that occurs in the human body and in some foods. MSM is an excellent dietary source of bioavailable organic sulfur.
The MSM Story – One of Nature's Primary Sources of Organic Dietary Sulfur!
The human body requires a continuous supply of usable sulfur, and MSM is one of the primary organic sulfur containing molecules for use by living organisms. From life's earliest beginnings, primitive marine organisms (blue-green algae and phytoplankton) have absorbed inorganic sulfur from ocean waters and produced organic sulfur molecules, primarily dimethyl sulfonium salts. These salts are released back into the sea, where they are converted to dimethyl sulfide, which readily evaporates, ending up in the upper atmosphere. Dimethyl sulfide is then oxidized by UV light, forming DMSO and MSM.
The two compounds are delivered to land masses in rain water, and absorbed by plants. MSM is a stable end product of this process, and thus serves as a primary source of sulfur in the food chain. Though present on earth since before life appeared on dry land, and known to science since the 1950's, MSM has only recently been recognized as having importance in human nutrition.
Why the Human Body Needs MSM
MSM occurs naturally in the blood, body fluids and tissues. It is now believed that a minimum MSM concentration of 0.2 parts per million is necessary for the body to function normally. MSM may be the most easily absorbed and nontoxic source of nutritional sulfur occurring in nature. Sulfur is a structural mineral that maintains the strength of various tissues by forming sulfur "tie-bars" (sulfhydryl bonds) between connective tissue proteins. MSM serves as a readily available source of sulfur for this function, and thus helps maintain the pliancy of tissues and cell membranes. Repair of damaged tissue depends upon a supply of sulfur for the continuation of reactions involving sulfhydryl groups (SH). Sulfur is required for the maintenance of healthy hair, skin and nails. In view of the presence of MSM in biological systems since the beginning of evolution, it is logical to assume that all higher life forms, including humans and animals, are well adapted to use MSM as a sulfur donor.
Clinical research on the role of MSM in the human body has culminated in the filing of several patents covering numerous uses for MSM as a dietary ingredient for both humans and animals. As a result of these investigations, it is believed that physical and psychological stress increases in the human body when the MSM concentration falls below minimum levels, resulting in a loss of normal organ function.
Based on observations, ingestion of MSM by humans has the following beneficial effects:
- MSM supports maintenance of strong, healthy body tissues by donating sulfur for formation of sulfur tie-bars between connective tissue proteins.*
- MSM supports normal gastrointestinal function.*
- MSM improves the body's resistance to adverse physical stress.*
- MSM supports mental alertness and maintenance of healthy mood.*
- MSM promotes the body's processes that heal tissue.*
- MSM helps modify the physiologic response to allergens.*
- MSM supports normal lung function.*
- MSM supports normal relaxation of muscles.*
- MSM supports normal joint function.*
- MSM helps maintain healthy skin.*
Supplementation is Needed to Realize the Benefits of MSM
Widespread in nature, MSM is found in a variety of foods, including fresh fruits and vegetables, raw milk, raw meat and raw fish. However, MSM is a volatile substance easily lost during cooking, pasteurization, food processing and storage. The average American diet thus supplies at best a marginal MSM intake, which may be inadequate to maintain the optimum MSM concentration in the body. The body's MSM concentration is also believed to decline with increasing age.
Effective dosages for the various reported uses of MSM range from 500 mg to 6 grams per day. 1000 mg per day is recommended to restore normal MSM concentrations, while higher doses may be necessary for specific uses.
MSM is considered to be as non-toxic to the body as water and is, therefore, completely safe at the higher dosage levels.
- Jacob, S., Herschler, R. Annals of the New York Academy of Sciences 1983; 411:xiii-xvii.
- Herschler, R. United States Patent 4,514,421; April 30, 1985.
- Herschler, R. United States Patent 4,616,039; October 7, 1986.
- Sellnow, L. The Blood Horse, June 6, 1987:3459-3462.
- Lawrence, R.M. International Journal of Anti-Aging Medicine 1998;1(1):50
- Jacob, S.W., Lawrence, R.M., Zucker, M. 1999. New York: G.P. Putnam's Sons.
| Q1. |
What is your MSM made of? Is it natural or synthetic? |
| A1. |
It is synthetic. OptiMSM is made by converting DMSO (dimethylsufloxide) which is an organosulfur compound (organic compound containing sulfur), to DMSO2. ALL commercially available MSM is manufactured, because amounts found in nature are too small to be extracted. |
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| Q2. |
Why did you switch from Lignisul/natural to OptiMSM/synthetic? |
| A2. |
We recently switched raw material suppliers from Lignisul MSM to OptiMSM. The reasons for this change included consistency of supply and clinical trial support specifically using OptiMSM. Lignisul MSM is still effective MSM and was used successfully by Doctor's Best for years. Lignisul is a premium product and is 99.9% pure. Lignisul MSM is made in the US and is natural.
On the other hand, the OptiMSM is manufactured in the US by a manufacturer solely producing MSM. OptiMSM is produced by oxidizing DMSO. This process parallels the natural oxidation of DMSO to MSM that occurs in the marine atmosphere and produces MSM that is chemically identical to that found in nature. The most important reason for the change is consistency of supply so it can be available to our customers without pause. |
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| Q3. |
What is the difference between MSM and sulfur? |
| A3. |
MSM and sulfur are not one and the same thing. MSM is an organic substance that contains bioavailable sulfur. MSM is not pure sulfur. It contains about 34 percent elemental sulfur. 1000 mg of MSM contains about 340 milligrams of elemental sulfur. (250 grams of MSM powder weighs 8.75 ounces.) |
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| Q4. |
What if I’m allergic to sulfur, sulfa drugs or sulfites and sulfates? Can I take MSM? |
| A4. |
Yes, according to the experts on MSM. MSM is not a sulfate or a sulfite. It is completely different from sulfa drugs, sulfites and sulfates. |
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| Q5. |
Is MSM related to or does it contain caffeine? |
| A5. |
No |
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| Q6. |
I have just opened a new bottle of MSM powder and it is very hard, is this normal? |
| A6. |
Yes. There are 3 reasons why MSM powder clumps:
a.)Â The bottle has remained inactive (in the same position) for a period of time. Simply shake the bottle vigorously until the clump breaks apart. Crushing the lumps with a spoon is also effective.
b.) The MSM powder contains no Excipients such as magnesium silicate, silicon dioxide or stearic acid to separate it and so it tends to try and revert to its natural state (solid) by clumping.
c.) Once a jar of MSM powder has been opened, it is susceptible to clumping due to humidity. Again, the solution is to simply shake the jar until the clumps disappear. |
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| Q7. |
I just opened my jar of MSM powder and found that it contains a large pouch, what is this and what are the benefits of having this in the jar? |
| A7. |
MSM is relatively "hydrophilic," meaning that it tends to draw water to itself. That is why DRB puts a large "desiccant" into the jar, which attracts water even more than does the MSM.
Some companies coat the MSM with excipients such as magnesium silicate or talc, which reduces or prevents the clumping. We chose not to add anything because when the powder is mixed with water, the magnesium silicate or talc does not dissolve. It just sits on the top of the water. This appears very unattractive. The OptiMSM MSM which DRB uses dissolves completely. |
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| Q8. |
What are the contraindications to MSM? |
| A8. |
According to the PDR for Nutritional Supplements, there are no known contraindications for MSM, except that it should not be used by pregnant and nursing mothers. (This is a general precaution that is applied because MSM has not been proven safe in pregnancy, not because it is known to be unsafe.) If taking blood-thinning medications or aspirin on a regular basis, consulting your physician to determine if a lower starting dose of MSM is recommended. Some people may experience mild gastrointestinal bloating, constipation or indigestion (Kim et al. 2006). |
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| Q9. |
I am somewhat confused on how to take the DRB products. On many of the labels the Suggested Adult Use will list something along the lines of: Take 2 capsules daily, but it does not state whether they should be taken together or separately. What is the correct usage? |
| A9. |
Unless otherwise specified on the label, the product may be taken together or separately. |
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| Q10. |
Is there a limit to how many vitamins can be taken safely in one day? |
| A10. |
While our bodies need vitamins and minerals, like other things, if taken in large amounts they may adversely affect health. Large amounts of anything can be toxic. It is important to follow all label directions and discuss any concerns with your physician. |
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| Q11. |
What are the other ingredients and why are they used? |
| A11. |
These are used as flow agents and aid in the production to keep the machinery running smoothly and the capsules filling correctly. Similarly for the croscarmellose sodium, which is cellulose (sourced from the cell walls of green plants), and is used to help disintegrate the tablet in the stomach. |
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| Q12. |
Since Doctor's Best does not manufacture its supplements, how are the purity and integrity of supplements verified? In addition, how are your prices lower than other brands? Does this mean that quality is being compromised? |
| A12. |
Doctor's Best supplements are manufactured in the US at cGMP (current Good Manufacturing Practice) certified facilities. All of our manufacturers and suppliers go through our vendor qualification program, which includes inspections and testing, before we agree to work with them. Our finished products have also been tested at the raw material level, in process, and as a finished product to ensure safety and quality. We place the highest importance on safety and quality and do not compromise for the sake of a better price point. The price points are lower because of production size and the overall business structure. We also place great importance on making our supplements available and affordable to those who need them most. |
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| Q13. |
What is HPLC? |
| A13. |
HPLC stands for "High Performance Liquid Chromatography." This is an analytical lab testing method that is used to quantify the active ingredients. It is considered to be a very sensitive and accurate test. HPLC testing is a tool recognized as a quality benchmark for herbal extracts. |
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| Q14. |
How is OptiMSM purified? |
| A14. |
Through distillation. |
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