L-Arginine 500mg

120 Tablets

DRB-00200

Health interest: Sports Nutrition , Heart Health
  • Doctor’s Best Sustained Plus Immediate Release Arginine is an unique formula with L-Arginine in two forms, immediate & sustained.

  • L-arginine has been shown to support the cardiovascular system, through its conversion to nitric oxide and may also have positive benefits on recovery from athletic performance.*

  • Two tablets of Doctor’s Best Sustained Plus Immediate Release Arginine delivers 1000mg L-arginine in a bilayer tablet, providing 500 mg of sustained release and 500 mg of immediate release L-arginine.

  • This technology allows for enhanced blood levels of L-arginine for a continuous period of up to 8 hours.

  • Non-GMO/ Gluten Free/ Soy Free/ Vegetarian/ Vegan

Available Sizes

120 Tablets

Buy Now

amazon.com iherb.com luckyvitamin.com vitacost.com swansonvitamins.com Find A Store Near You

What is Doctor’s Best Sustained Plus Immediate Release Arginine?

Doctor’s Best Sustained Plus Immediate Release Arginine promotes a healthy cardiovascular system, enhances healthy circulation and supports heart function.* L-arginine has been shown to support the cardiovascular system, through its conversion to nitric oxide.* Research suggests L-arginine supplementation may also have positive benefits on athletic performance.* Two tablets of Doctor’s Best Sustained Plus Immediate Release Arginine delivers 1000mg L-arginine in a bilayer tablet, with two tablets providing 500 mg of sustained release and 500 mg of immediate release L-arginine. This technology allows for enhanced blood levels of L-Arginine for a continuous period of up to 8 hours.*

How does it work?

Oral L-arginine supplementation has been shown in clinical studies to support various aspects of cardiovascular health. A randomized double-blind placebo-controlled trial found that six weeks of L-arginine supplementation enhanced circulation and supported healthy heart function compared to placebo.* The L-arginine effect was due to its role in NO production. Other clinical trials have shown that oral L-arginine supplementation contributes to enhanced exercise tolerance because of its ability to enhance cardiac circulation and vasodilation of blood vessels.* L-arginine enrichment of the diet in healthy individuals was shown to support blood pressure already in the normal range.* The overall results of these and other clinical trials showed that long-term administration of this amino acid significantly enhanced endothelial function.*

Why take Sustained and Immediate Release Arginine?

The normal aging process in humans has been found to be associated with progressive changes in endothelial function (cells that line the inner surfaces of blood vessels). Research suggests that a major reason for these common changes associated with aging is reduced production or bioavailability of nitric oxide (NO) in vessels and tissues. L-arginine is a substrate for the enzyme nitric oxide synthase, required for the production of nitric oxide in the body. Nitric oxide is a substance critical for the maintenance of normal vascular function. NO mediates a number of physiological effects on the cardiovascular system, including supporting healthy endothelial function, enhancing cardiovascular health and displaying potent antioxidant properties against free radicals.

Why do you suggest taking Sustained Plus Immediate Release L-Arginine away from food? I have seen other brands that suggest taking it with food.

The idea behind taking arginine away from food is that arginine may have to compete with other amino acids found in food for absorption. For example, lysine has been reported to compete with arginine's absorption in the intestine, as well as transport into cells. It also may compete for reabsorption in the renal tubules, resulting in increased arginine excretion (Gaby 2011).

What is the country of origin for Doctor's Best products?

Doctor’s Best products are quality tested and manufactured in the United States using highly qualified cGMP manufacturers and raw material ingredients. Doctor’s Best sources raw materials from around the world and ingredients are subject to the intense testing and verification regardless of geography of origin.

Consult your healthcare provider before use if you are taking any prescription medications or if you have a medical condition.

Information

What is Doctor’s Best Sustained Plus Immediate Release Arginine?

Doctor’s Best Sustained Plus Immediate Release Arginine promotes a healthy cardiovascular system, enhances healthy circulation and supports heart function.* L-arginine has been shown to support the cardiovascular system, through its conversion to nitric oxide.* Research suggests L-arginine supplementation may also have positive benefits on athletic performance.* Two tablets of Doctor’s Best Sustained Plus Immediate Release Arginine delivers 1000mg L-arginine in a bilayer tablet, with two tablets providing 500 mg of sustained release and 500 mg of immediate release L-arginine. This technology allows for enhanced blood levels of L-Arginine for a continuous period of up to 8 hours.*

How does it work?

Oral L-arginine supplementation has been shown in clinical studies to support various aspects of cardiovascular health. A randomized double-blind placebo-controlled trial found that six weeks of L-arginine supplementation enhanced circulation and supported healthy heart function compared to placebo.* The L-arginine effect was due to its role in NO production. Other clinical trials have shown that oral L-arginine supplementation contributes to enhanced exercise tolerance because of its ability to enhance cardiac circulation and vasodilation of blood vessels.* L-arginine enrichment of the diet in healthy individuals was shown to support blood pressure already in the normal range.* The overall results of these and other clinical trials showed that long-term administration of this amino acid significantly enhanced endothelial function.*

Why take Sustained and Immediate Release Arginine?

The normal aging process in humans has been found to be associated with progressive changes in endothelial function (cells that line the inner surfaces of blood vessels). Research suggests that a major reason for these common changes associated with aging is reduced production or bioavailability of nitric oxide (NO) in vessels and tissues. L-arginine is a substrate for the enzyme nitric oxide synthase, required for the production of nitric oxide in the body. Nitric oxide is a substance critical for the maintenance of normal vascular function. NO mediates a number of physiological effects on the cardiovascular system, including supporting healthy endothelial function, enhancing cardiovascular health and displaying potent antioxidant properties against free radicals.

Supplemental Facts

FAQs

Why do you suggest taking Sustained Plus Immediate Release L-Arginine away from food? I have seen other brands that suggest taking it with food.

The idea behind taking arginine away from food is that arginine may have to compete with other amino acids found in food for absorption. For example, lysine has been reported to compete with arginine's absorption in the intestine, as well as transport into cells. It also may compete for reabsorption in the renal tubules, resulting in increased arginine excretion (Gaby 2011).

What is the country of origin for Doctor's Best products?

Doctor’s Best products are quality tested and manufactured in the United States using highly qualified cGMP manufacturers and raw material ingredients. Doctor’s Best sources raw materials from around the world and ingredients are subject to the intense testing and verification regardless of geography of origin.

Safety

Consult your healthcare provider before use if you are taking any prescription medications or if you have a medical condition.