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Betaine HCl Pepsin & Gentian Bitters

120 Capsules DRB-00163

Natural relief.

Just what the doctor ordered. Betaine HCI, Pepsin & Gentian Bitters from Doctor’s Best features three nutritional factors designed to support your digestive process.* These complimentary ingredients work in tandem to break down food, as well as ease occasional gas and bloating.* Take this supplement with food, three times a day, to maintain proper digestive function and overall health.* A long name...for fast-acting relief.

  • Non-GMO
  • Gluten Free
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Wonderful for acid reflux. I'm very prone to acid reflux and heartburn and after many years of antacids making the problem worse I figured my stomach acids weren't acidic enough, so I, very reluctantly, gave this a try. I'm soooo.... Glad I did!!! It's been wonderful. I take it with foods I'm more prone to get acid reflux with (such as dairy) and no acid reflux or heartburn. And sometimes I take it after I eat (after I already have acid reflux) and in about 15-30 minutes it's gone.

Reviewed in the United States on November 27,

Love this supplement. This has been the answer to my IBS and food allergies. Now I eat everything and HCL does its job - no more heartburn either. Love this supplement.

Reviewed in the United States on February 22,

Great product. Started using HCL after experiencing heartburn for the first time in 45 years of living, the horror! After taking this product I have not had another episode of heartburn and I am thrilled. The first couple of times I took 4 capsules at once with my meal and it that turned out to be the right dose for a few days, then apparently my stomach acid started to balance out and I lowered the dose to two with each meal. Now I only take a few times a week with higher protein meals and will continue. Great product.

Reviewed in the United States on February 18,
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Time-tested and approved.

Betaine HCI, Pepsin & Gentian Bitters is thoughtfully formulated with natural ingredients to ease digestive discomfort.* Native to parts of Europe and Asia, Gentian is an herb that has been used extensively by traditional herbalists - due to its bitter constituents that assist in digestion. Gentian has also been shown to encourage gastric secretions, as well as promote choleretic activity.*

Suggested Use 

Each serving contains 650 mg of betaine HCI, 250,000 FCC units of pepsin, and 20 mg of gentian. Take one capsule three times daily, with food.


Betaine hydrochloride is a source of hydrochloric acid, a naturally occurring chemical in the stomach that helps digest food by breaking up fats and proteins.

Do not confuse pepsin with PepZin GI. Pepsin is a digestive enzyme, whereas PepZin GI is a trademarked compound consisting of zinc and l-carnosine.

Betaine HCI is made through chemical synthesis.

Doctor's Best products are quality tested and manufactured in the United States using highly qualified cGMP manufacturers and raw material ingredients. Doctor's Best sources raw materials from around the world and ingredients are subject to the intense testing and verification regardless of geography of origin.

Doctor's Best products can be found at vitamin specialty, chain and independent natural product stores across the country, as well as online. We recommend that you use our online Where to Buy store finder to find a store near you or one of our online partners who can ship to you directly.