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Glucosamine Chondroitin MSM + Hyaluronic Acid

150 Capsules DRB-00271

Do it all. 

Healthy joints are essential to move freely and without discomfort. Wellness seekers turn to glucosamine to assist with this.*  Our formula provides a powerful combination of three proven, purified ingredients to stimulate the production of proteoglycans in joints.* Chondroitin, a building block of cartilage, helps joints stay lubricated and promotes overall joint comfort.* We  also added OptiMSM®, which supplies natural, easy-to-absorb sulfur in the purest form.* Keep yourself moving with a daily dose of Glucosamine Chondroitin MSM.*

  • Non-GMO
  • Gluten Free
  • Soy Free
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I had some hip and leg pain that was preventing me from getting back on a running routine. This product resolved those issues in about two weeks. Also, the hyaluronic acid helped my skin look healthier. I was going to pay more money at Costco for multiple products, with lower dosages... I will purchase this again. I am always satisfied with Doctor’s Best products and recommend them to everyone.

Reviewed in the United States on December 13,

Whenever I run out of these and don't take them for more than four to five days, boy do my knees feel it. I have osteoarthritis, and X-rays show the problem is not mild. And still these work so well, I have no pain while taking them.

Reviewed in the United States on January 20,

This works great. This is my second bottle and I am able to walk on my treadmill daily because of it. Would definitely recommend it!

Reviewed in the United States on November 23,

My doctor has been pushing me to have both knees replaced for five years, but I'm waiting for a better option. These pills have been a godsend. I can't stand for more than 15 minutes without them. I really notice the difference when I run out. I can't find these anywhere but Amazon. Thank you. I really trust this brand for quality and consistency.

Reviewed in the United States on June 10,
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BioCell Collagen® for the win.

We chose American-manufactured OptiMSM® for our formulas because it is the purist and only form of MSM on the market that is GRAS-designated (Generally Recognized as Safe). It achieved this designation by adopting a four-stage process to separate impurities including heavy metals and other contaminants. Each batch exceeds the United States Pharmacopeia (USP) monograph standards for MSM, and is validated by testing in independent laboratories.

Suggested Use

Each serving contains 1,500 mg of glucosamine sulfate, 1,000 mg of chondroitin sulfate, 1,000 mg of OptiMSM® and 1,000 mg of BioCell Collagen®. Take five capsules daily with food.


Doctor's Best Hyaluronic Acid with Chondroitin Sulfate features BioCell Collagen that is standardized to 20% Chondroitin Sulfate and 10% Hyaluronic Acid, in addition to approximately 60% Collagen Type II. BioCell Collagen is sourced from the sternal cartilage of chickens that are raised without hormones or steroids present in the poultry feed.

No, it does contain a small amount of sodium. Sodium must be added during processing.

Yes, it is completely different from sulfa drugs, sulfites and sulfates.

MSM is an organic substance that contains bioavailable sulfur. MSM contains about 34 percent elemental sulfur. 1000 mg of MSM contains about 340 milligrams of elemental sulfur.

MSM is not commercially available as an extract from plants or other natural materials. OptiMSM is made by converting DMSO (dimethylsufloxide) which is an organosulfur compound (organic compound containing sulfur), to DMSO2.

Through distillation.

Doctor's Best uses OptiMSM, a premium trademarked form of MSM, made in the USA and certified for quality and consistency.

Doctor's Best products are quality tested and manufactured in the United States using highly qualified cGMP manufacturers and raw material ingredients. Doctor's Best sources raw materials from around the world and ingredients are subject to the intense testing and verification regardless of geography of origin.

Doctor's Best products can be found at vitamin specialty, chain and independent natural product stores across the country, as well as online. We recommend that you use our online Where to Buy store finder to find a store near you or one of our online partners who can ship to you directly.